What is PDGF?

Platelet-derived growth factor (PDGF) is a naturally occurring protein found in human blood, platelets, embryonic tissues, and bone. It plays a vital role in cellular growth, tissue repair, and wound healing.

Recombinant PDGF has been safely used in medicine for over 15 years in orthopedic, periodontal, and maxillofacial surgery, helping more than five million patients heal faster and stronger.

In aesthetics, PDGF stimulates the body’s natural repair processes by:

  • Activating stem cells, fibroblasts, and smooth muscle cells

  • Promoting the formation of new blood vessels

  • Stimulating collagen and elastin production

  • Supporting extracellular matrix components (including hyaluronic acid and glycosaminoglycans)

The result: healthier, firmer, and more resilient skin with improved circulation and reduced inflammation.

What is Pure PDGF+?

Ariessence® Pure PDGF+ is a next-generation regenerative treatment that delivers pharmaceutical-grade, sterile PDGF combined with hyaluronic acid. By combining the powerful regenerative properties of platelet-derived growth factor (PDGF) with hyaluronic acid, this advanced treatment offers a safe and effective way to restore youthful, glowing skin.

How does Pure PDGF+ work?

Immediately following an advanced procedure such as microneedling or fractional laser, the skin is in its most receptive state. Pure PDGF+ is applied during this “golden window,” allowing growth factors to penetrate deeply, enhancing cellular renewal and accelerating natural rejuvenation.

The unique pairing of recombinant PDGF and hyaluronic acid begins working within minutes, signaling skin cells to repair, regenerate, and rebuild from within.

BenefitS:

  • Boosts collagen production for firmer, more youthful skin

  • Reduces fine lines & wrinkes, softening visible signs of aging

  • Minimizes scars with healthy collagen remodeling for a smoother skin surface

  • Increases skin hydration by strengthening the skin barrier for better retention

  • Promotes cell turnover for a radiant, even skin tone leading to a brighter complexion

  • Enhances healing and reduces downtime after laser and microneedling treatments

  • Improves hollows and dark circles with under-eye rejuvenation

  • For hair restoration it stimulates scalp health, reduces inflammation, and supports stronger, fuller hair growth

How does Pure PDGF+ differ from PRP?

Traditional PRP (platelet-rich plasma) treatments require drawing the patient’s blood, isolating plasma through centrifugation, and re-injecting it into the skin or scalp. While PRP can be effective, results are often inconsistent, since quality depends on the patient’s blood that day. PRP is also more invasive, time-consuming, and sometimes uncomfortable.

Unlike patient-derived growth factors, Ariessence® Pure PDGF+ is standardized, consistent, and potent—containing up to 300,000 more growth factors per application compared to PRP.

Summarized:

  • Requires no blood draw

  • Delivers a consistent, pharmaceutical-grade concentration every time

  • Contains up to 300,000 more growth factors per application than PRP

  • Provides a standardized, sterile, and potent solution for reliable results

How is a treatment performed?

Pure PDGF+ is not a standalone facial—it’s an enhancement. It is paired with procedures like microneedling or laser treatments.

Immediately following an advanced treatment, Pure PDGF+ is applied to the skin at its most receptive state.

Who is a good candidate?

Pure PDGF+ is suitable for individuals who want to:

  • Improve skin tone, texture, and radiance

  • Reduce fine lines, wrinkles, or scars

  • Accelerate healing and enhance results after procedures

  • Brighten dull or uneven skin

  • Strengthen and restore thinning hair

  • Seek a consistent alternative to PRP

Frequency of Treatments

Pure PDGF+ is designed to be used immediately post-procedure to enhance recovery and results.

Microneedling with PDGF: 2–4 sessions spaced 4–6 weeks apart

Hair Restoration: 4–6 treatments spaced 4–6 weeks apart, with maintenance every 4–6 months

 

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